Path of Exile Wiki

Please consider helping keep the wiki up to date. Check the to-do list of updates needed for version 3.14.0.

Game data exports will becoming later as the technical changes in addition to regular changes take some more time.


Path of Exile Wiki
Profane Chemistry
Notable Passive Skill
ProfaneChemistry passive skill icon.png
6% increased maximum Life
30% increased Life Recovery from Flasks
Flasks applied to you have 8% increased Effect [1]

Profane Chemistry is a notable passive skill that grants increased maximum life. It grants increased life recovery from flasks. It also grants an effect that increases the effect of flasks applied to the character.

Version history

Version Changes
  • The area surrounding the Witch, Shadow and Ranger has been redesigned. Many clusters throughout the tree now have new notables.
  • Percentage-based life increases have been reduced slightly and redistributed more evenly through the tree.